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In this Review, we describe mechanisms by which the gut and brain communicate and highlight human and animal studies that implicate changes in gut-brain communication in disease states in gastroenterology, neurology, psychiatry, and endocrinology

e071725e071725, www.bmj.com/content/383/bmj-2022-071725, Julian, Thomas, et al

It may be difficult to determine the exact time when your vitamin B12 injections have started working, as many people will report noticing a difference in their energy levels within a few days following the shot, and others may not feel the increase in energy for multiple weeks if their body needs the vitamin to build up a bit more

A vendor unwilling to publish HPLC/MS results for the batch you're buying has nothing to verify their purity claim against